Dnipro hit by ICBM, attacks elsewhere in Ukraine kill 3, injure 22.

Editor’s note: The article was updated with the Air Force’s report about Russia using an intercontinental ballistic missile.
Russian forces launched a large-missile missile attack early on Nov. 21, reportedly lifting Tu-95 bombers and MiG-31K Kinzhal carriers and attacking the central-eastern city of Dnipro.
Russia attacked Dnipro with an intercontinental ballistic missile (ICBM), a Kh-47M2 Kinzhal air-launched ballistic missile, and seven Kh-101 cruise missiles, the Air Force said. Six of the Kh-101 missiles were reportedly shot down.
This marks the first instance of Russia using an ICBM in its war against Ukraine.
An industrial enterprise was damaged, and two fires broke out in the city, Governor Serhii Lysak said. A rehabilitation center for people with disabilities was damaged in the attack, Mayor Borys Filatov said.
No casualties were reported at the moment.
Elsewhere across the country, Russian attacks killed at least three people and injured at least 22 over the past day, including a child, authorities reported.
In Donetsk Oblast, a Russian attack against the village of Pershomarivka killed one person and injured two, Governor Vadym Filashkin reported. Six people were reportedly injured during an attack against the town of Kostiantynivka.
Russian attacks against Kherson Oblast overnight and on Nov. 20 killed one person and injured 10, including a child, according to Governor Oleksandr Prokudin. A 62-year-old woman was also killed during an attack against the Darivka village on the morning of Nov. 21, the governor said.
In Kharkiv Oblast, a 64-year-old woman was injured in an attack against the village Vysokyi, and two men aged 42 and 64 were wounded in strikes against the town of Kupiansk, Governor Oleh Syniehubov reported.
A civilian was injured during Russian attacks against the Krasnopillia community in Sumy Oblast, the regional military administration said.